eProtein Discovery™ Overview

Nuclera eProtein Discovery™ System is the only end-to-end protein prototyping system that accelerates construct design, expression, solubility characterization and purification of target proteins in drug discovery programs. Accelerating the journey to your protein.

Rapid protein prototyping enables progress by allowing scientists to gain awareness quickly about which proteins – and which variations of a protein – will work.
Simultaneously screen multiple constructs and protein synthesis reagents for soluble expression and purification, then scale up to micrograms of recombinant protein off cartridge to test in your applications.
Explore multiple DNA constructs, including solubility tags, polymorphisms and isoforms on the same cartridge to expand your range of accessible proteins.

One complete protein solution.

Instrument: With protein prototyping, you can draw a straight line from theory to reality, allowing you to test hypotheses more efficiently and focus on promising targets. The eProtein Discovery™ instrument puts rapid protein prototyping on your benchtop. Designed for all levels of scientist, it streamlines your workflow and grants you the ability to identify optimal DNA constructs, test expression feasibility earlier, and pursue targets with confidence. Fail fast, succeed faster!

Software: eProtein Discovery™ software simplifies a complex multivariate experimental design. The software sets up and simultaneously tracks up to 192 different combinations of DNA sequences, flank pairs and expression reagent reactions performed on eProtein Discovery™ system. AI performs highly rigorous QA checks during an experiment to ensure data quality and consistency. Informative reports are then generated and exported that you can share with your team and beyond.

Cartridge: Powered by digital microfluidic technology, software controlled digital signals guide the movement of droplets on the eProtein Discovery™ Cartridge surface to enable splitting, dispensing and merging of biological reagents. Pipette DNA, cell free expression reagents and purification solutions on the Cartridge and the technology will orchestrate the rest. Gain precise control of your eGene™ constructs and reagents to screen and discover optimal expressing conditions within 24 hours, accelerating target selection. A simple set-up allows anyone to run the system with minimal training.

Nuclera Technical Support:
UK Phone +44 1223 942 761
US Phone: +1 508-306-1297
Email: techsupport@nuclera.com

Offices:
Nuclera UK (HQ):
One Vision Park, Station Road, Cambridge, CB24 9NP, UK

Nuclera USA:
1000 Technology Park Drive, Suite B, Billerica MA 01821, USA

www.nuclera.com

One complete protein solution.​

One complete protein solution.